Common primary muscle disorders include inflammatory myopathies, including polymyositis, which is characterized by inflammation and progressive weakening of the skeletal muscles; dermatomyositis, which is polymyositis accompanied by a skin rash; and inclusion body myositis, which is characterized by progressive muscle weakness and wasting. Other common disorders are muscular dystrophies and metabolic muscle disorders, he said. Muscular dystrophy affects muscle fibers. Metabolic muscle disorders interfere with chemical reactions involved in drawing energy from junction disorders impair the transmission of nerve signals to muscles, Schabbing noted.
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As far as changes to the program, I found doing 5x5 deadlifts to be excessive in the novice version (completely drained me) and ramp-up 1x5 DLs worked better (a la Rippetoe/SS). If you still need more DL volume for whatever reason, I've lately tacked on 5x10 on the last day after the other exercises with 30-50% 1RM weight (a la Wendler/531's Boring But Big). Also needed to add extra arm work. Calves were a lagging issue for me BUT the sheer amount of squats made them come up naturally. Otherwise, this is perfect. Stick to this protocol with adequate rest, good form and a slight caloric surplus and you'll be somewhere strong in no time.