Given there’s no long-term data with topical NSAIDs, the evidence doesn’t give us enough insight to understand the risk profile beyond a few weeks. Consequently it seems reasonable to try using topical products instead of oral products, particularly for intermittent, rather than chronic, pain conditions. While compounding pharmacies have made topical versions of NSAIDs for years, there’s little information on effectiveness and safety of these products. As commercial formulations are supported with pharmacokinetic and clinical studies demonstrating efficacy, they are the preparations of choice.
One of the major economic and cultural hubs of South America, Rio de Janeiro is a cosmopolitan metropolis, known worldwide for its scenic beauty and its natural resources. The city receives more than 2 million international tourists each year. The official and most widely spoken language is Portuguese.
With its ample infrastructure of tourism services, Rio de Janeiro ranks among the top destinations in the world for cultural, commercial, technical, and scientific events. Its exuberant natural resources include 90km of beaches, the Tijuca National Park including the largest urban forest in the world, three state parks, and many beautiful lakes and lagoons.
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