These eye drops and ointments contain a combination of a steroid and one or more types of antibiotic for treatment of infection and inflammation of the eye. The steroid reduces inflammation while the antibiotic treats or prevents infection which may be the cause of the infection. Examples of steroids that are used in these eye drops are hydrocortisone, loteprednol, prednisolone, and dexamethasone . Examples of antibiotics used in these formulations include tobramycin, neomycin, bacitracin, polymixin B, and gentamycin. These antibiotics have different mechanisms of action and two or three may be combined in one formulation.
Lotemax is used in dry eye syndrome to decrease and eliminate inflammation of the ocular surface caused by the hyperosmolarity of the tears. The inflammation must first be brought under control before any other treatments can be optimally effective. Lotemax would typically be prescribed for two weeks to three months initially and then may need to be used again on a 1-2 week regimen periodically if the inflammation occurs again. Lotemax ointment has become a choice of many doctors to treat inflammation caused by dry eye (ocular surface disease) because it can be used at night with a long contact period to the eye's surfaces and provide some functional lubrication while the eyes are closed.
Many published health-care–associated EKC outbreaks have had simultaneous community transmission ( 1–3 ); however, prevention and control efforts have focused on health-care settings. Among the six outbreaks described in this report, five occurred in outpatient settings, health-care providers were likely sources of transmission in four, and infection control breaches were noted in all. Clinicians in all health-care settings are expected to follow basic infection control practices, including standard precautions ( 5 ). These expectations for outpatient settings are emphasized in a recent summary of CDC guidance .*