Steroid hormone synthesis mnemonic

Cells of the zona fasciculata and zona reticularis lack aldosterone synthase (CYP11B2) that converts corticosterone to aldosterone, and thus these tissues produce only the weak mineralocorticoid corticosterone. However, both these zones do contain the CYP17A1 missing in zona glomerulosa and thus produce the major glucocorticoid, cortisol. Zona fasciculata and zona reticularis cells also contain CYP17A1, whose 17,20-lyase activity is responsible for producing the androgens, dehydroepiandosterone (DHEA) and androstenedione. Thus, fasciculata and reticularis cells can make corticosteroids and the adrenal androgens, but not aldosterone.

The question of product integrity is always central in the minds of BM customers, “Can I purchase safe products from this source?” The virtually anonymity of internet sites coupled with traditionally high provider turnover rates has made answering this question even harder in today’s society. The BM is filled with “scammers”, individuals who simply set up shop to dupe customers out of money with no plan or intention of delivering on the promised AAS. These are actually the good guys, those who promote the once bitten syndrome and scare many would-be buyers/users away from further attempts at steroids. At least they have the decency (used lightly) to take your money and run. Numerous dealers run repackaging scams in which very cheap steroids are placed in expensive product labeling and sold at a premium. These less expensive forms of AAS produce greater side effects, which can be particularly dangerous to women who think they are buying a very mild steroid only to receive a significantly harsher product. Still others produce imposter or fake steroids, which are often bottles of vegetable oils labeled to look like AAS. Along the same lines are those manufactured under conditions that are far less sanitary than required by the FDA. All of the above hazards can lead to health problems ranging from minor such as abscesses and infections, to major like severe illness and death.

The most commonly used AAS in medicine are testosterone and its various esters (but most commonly testosterone undecanoate , testosterone enanthate , testosterone cypionate , and testosterone propionate ), [53] nandrolone esters (most commonly nandrolone decanoate and nandrolone phenylpropionate ), stanozolol , and metandienone (methandrostenolone). [1] Others also available and used commonly but to a lesser extent include methyltestosterone , oxandrolone , mesterolone , and oxymetholone , as well as drostanolone propionate , metenolone (methylandrostenolone), and fluoxymesterone . [1] Dihydrotestosterone (DHT; androstanolone, stanolone) and its esters are also notable, although they are not widely used in medicine. [54] Boldenone undecylenate and trenbolone acetate are used in veterinary medicine . [1]

Steroid hormone synthesis mnemonic

steroid hormone synthesis mnemonic

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