Progestins are steroid hormones that are typically prescribed to postpone heat cycles or alleviate false pregnancies in female dogs and treat benign prostatic hypertrophy in male dogs. They may also be used for some types of skin problems or to modify aggressive behavior. Megestrol acetate and medroxyprogesterone are the most commonly used progestins in dogs. Potential side effects include increased thirst and appetite, behavioral changes, mammary gland enlargement, and an increased likelihood of developing diabetes mellitus, acromegaly (a hormonal disease that causes enlargement of the head), Cushing’s disease, uterine infection (pyometra), reproductive disorders, and some types of cancer.
Stanley’s allergy tests identified a list of food, insect, and inhalant al lergens, including chicken, carrots, rice, grains, fleas and flea saliva, cats and cat dander, mold, grasses, and trees. Schaff eliminated what allergens she could and used topical medications and the corticosteroid Prednisone to treat Stanley’s remaining symptoms. The topicals did not work, and the pharmaceuticals gave the dog polyuria/polydipsia (PU/ PD), a condition causing excessive thirst and passage of large volumes of urine. Added to his misery of itchy raw spots, weepy lesions, and a stinky, gooey coat, poor Stanley was now having frequent and unavoid able accidents.